Lymphoma

  • Hodgkin Lymphoma (HL):
    • Characterized by the presence of a specific type of cell called Reed-Sternberg cells.
    • Tends to occur in younger people but can affect anyone.
  • Non-Hodgkin Lymphoma (NHL):
    • More common than Hodgkin lymphoma
    • Involves various types of lymphoma, each with different behaviors

Risk Factors

  • Age: Risk increases with age, particularly for NHL.
  • Weakened immune system: Conditions like HIV, organ transplants, or autoimmune diseases can increase the risk.
  • Infections: Certain infections like Epstein-Barr virus (EBV) or Helicobacter pylori can be linked to lymphoma development.
  • Family history: Having a close family member with lymphoma can increase your risk.

Symptoms

 Lymphoma symptoms can vary, but common signs include:

  • Painless swelling of lymph nodes (in the neck, armpits, or groin)
  • Fatigue and unexplained weight loss
  • Night sweats and fevers
  • Itchy skin and shortness of breath
  • Pain or swelling in the abdomen if the spleen or liver is affected

Diagnosis

 Diagnosing lymphoma usually involves:

  • Physical exam to check for swollen lymph nodes.
  • Blood tests to look for abnormal cell counts.
  • Biopsy (removing a small sample of tissue) of the lymph node to check for cancerous cells.
  • Imaging tests like CT scans, PET scans, or MRI to determine the spread of the disease.

Treatment

 Treatment depends on the type and stage of lymphoma:

  • Chemotherapy: Often the primary treatment for most types of lymphoma.
  • Radiation therapy: Used to treat localized lymphomas or after chemotherapy.
  • Targeted therapies: Drugs designed to attack specific lymphoma cells.
  • Immunotherapy: Boosts the body’s immune system to fight cancer.
  • Stem cell transplant: For more advanced cases or relapse.